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CAS No. | 154639-24-4 | Cat. No. | BCP44603 |
Name | TAN 1364B | ||
Synonyms | RK-682 (rac-1); Streptomyces sp.; | ||
SMILES | CCCCCCCCCCCCCCCC(=O)C1=C(C(OC1=O)CO)O | ||
Chemical Name | |||
Formula | C21H36O5 | M. Wt | 368.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682. TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B, but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium. TAN 1364B forms aggregates in solution and binds to both the PTP binding site and to protein surfaces. |
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