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TAN 1364B Chemical Structure

TAN 1364B

Data Sheet For research use only. Not for human use.
Cat. No. :BCP44603CAS No. :154639-24-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 154639-24-4 Cat. No. BCP44603
Name TAN 1364B
Synonyms RK-682 (rac-1); Streptomyces sp.;
SMILES CCCCCCCCCCCCCCCC(=O)C1=C(C(OC1=O)CO)O
Chemical Name
Formula C21H36O5 M. Wt 368.51
Purity 98% Storage Store at 4-8°C
Description TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682. TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B, but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium. TAN 1364B forms aggregates in solution and binds to both the PTP binding site and to protein surfaces.
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