Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Somatostatin Receptor
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
- Glucagon Receptor
- Prostaglandin Receptor
- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- mAChR
- P2 Receptor
- GPR
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Opioid Receptor
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- FAAH
- CGRP Receptor
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- ACC
- Xanthine Oxidase
- Pyruvate Kinase
- Mitochondrial Metabolism
- ALDH
- SCD
- Serine Protease
- MLR
- FTase
- CETP
- Neprilysin
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- PAI1
- NOX
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Azaindazole
- Pyridazine Series
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Boric acid
- Pyrimidine Series
- Quinoline Series
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Benzene Series
- Pyridine Series
Raw Materials
JNK
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
BCP24633 | JNK-IN-8 New | 1644498-56-5 | |
JNK-IN-8 is a potent JNK inhibitor with IC50s of 4.7 nM, 18.7 nM, and 1 nM for JNK1, JNK2, and JNK3, respectively.
|
BCP46470 | Brimapitide New | 1445179-97-4 | |
Brimapitide is a protease resistant, potent inhibitor specific for JNK (JNK1, JNK2 and JNK3).
|
BCP43705 | Indirubin-3'-oxime New | 667463-82-3 | |
Indirubin-3'-monoxime, a synthetic derivative of indirubin, is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Indirubin-3′-oxime directly inhibits the activity of all three isoforms of JNK (JNK1, JNK2, and JNK3), with IC50s of 0.8 μM, 1.4 μM, and 1.0 μM, respectively. Indirubin-3′-oxime can enhance height growth via activation of Wnt/β-catenin signaling in chondrocytes.
|
BCP38621 | CC-90001 New | 1403859-14-2 | |
CC-90001 is a potent and selective JNK inhibitor, which is 12.9-fold more potent for JNK1 inhibition than JNK2 in a cell-based model.
|
BCP35736 | Urolithin B New | 1139-83-9 | |
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
|
BCP34038 | DTP3 TFA New | DTP3 | |
DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kinase kinase 7) inhibitor.
|
BCP32871 | AS601245 New | 345987-15-7 | |
AS601245 is a cell-permeable JNK Inhibitor with IC50s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
|
BCP32078 | SU 3327 New | 40045-50-9 | |
SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK) (IC50 = 0.7 μM) with selectivity over p38 MAPK and Akt. SU 3327 inhibits the interaction between JNK and JIP (IC50 = 239 nM).
|
BCP17485 | IQ-1S | 23146-22-7 | |
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.
|
BCP25004 | CC-401 hydrochloride | 1438391-30-0 | |
CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.
|