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ALDH

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ALDH

Chemical Structure Cat. No. Product Name CAS No.
NCT-505 Chemical Structure
 BCP44645 NCT-505 2231079-74-4
NCT-505 is an Orally Bioavailable aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitor with Potent Cellular Activity (IC50 = 7 nM).
RV01 Chemical Structure
 BCP44644 RV01 1016897-10-1
RV01 is an analogue of resveratrol.
EN40 Chemical Structure
 BCP31630 EN40 2094547-67-6
EN40 is a potent, selective, and covalent ligand which inhibits aldehyde dehydrogenase 3A1 (ALDH3A1), and impairs lung cancer pathogenicity.
NCT-501 Chemical Structure
 BCP23989 NCT-501 1802088-50-1
NCT-501 is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 >57 μM).
Alda-1 Chemical Structure
 BCP17146 Alda-1 349438-38-6
Alda-1 is an ALDH2 agonist, cell-permeable activator of both the wild-type ALDH2*1 and the asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).
Disulfiram Chemical Structure
 BCP07331 Disulfiram 97-77-8
Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
CVT-10216 Chemical Structure
 BCP27995 CVT-10216 1005334-57-5
CVT-10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively).
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