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Autophagy

Chemical Structure Cat. No. Product Name CAS No.
MTX115325 Chemical Structure
 BCP49673 MTX115325 2750895-97-5
MTX115325 is an orally active, brain-penetrating USP30 inhibitor (IC50=12 nM) with neuroprotective activity.
SN-38-D3 Chemical Structure
 BCP49629 SN-38-D3 718612-49-8
SN-38-D3 is the deuterium labeled SN-38. SN-38 is an active metabolite of the Topoisomerase I inhibitor Irinotecan.
Mitophagy activator 1 Chemical Structure
 BCP49607 Mitophagy activator 1 2499962-58-0
Mitophagy activator 1 is an activator of mitophagy.
Tempol Chemical Structure
 BCP49192 Tempol 2226-96-2
Tempol is a general superoxide dismutase (SOD)-mimetic agent that efficiently neutralizes reactive oxygen species (ROS).
DL-Selenomethionine Chemical Structure
 BCP24111 DL-Selenomethionine 1464-42-2
DL-Selenomethionine is a selenium (Se) analogue of methionine in which sulfur is replaced with the trace element selenium.
SBP-7455 Chemical Structure
 BCP48924 SBP-7455 1884222-74-5
SBP-7455 is a potent, high affinity and orally active dual ULK1/ULK2 autophagy inhibitor with IC50s of 13 nM and 476 nM in the ADP-Glo assays, respectively. SBP-7455 potently inhibits ULK1/2 enzymatic activity and can be used for triple-negative breast cancer (TNBC) research.
CA77.1 Chemical Structure
 BCP48919 CA77.1 2412270-22-3
CA77.1 (CA) is a potent, brain-penetrant and orally active activator of chaperone-mediated autophagy (CMA) for the treament of Alzheimer's disease (AD).
Heparin calcium Chemical Structure
 BCP25407 Heparin calcium 37270-89-6
Heparin calcium is an injection form of heparin, a sulfated polysaccharide that has been used as a life-saving anticoagulant in clinics well before its detailed structure was known.
LYN-1604 dihydrochloride Chemical Structure
 BCP33963 LYN-1604 dihydrochloride 2310109-38-5
LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC).
FMK 9a Chemical Structure
 BCP48038 FMK 9a 1955550-51-2
FMK 9a is an autophagin-1 inhibitor with IC50 values of 80 and 73 μM in FRET and LRA assay.
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