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Syk

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Syk

Chemical Structure Cat. No. Product Name CAS No.
MK8457 Chemical Structure
 BCP23883 MK8457 1312518-84-5
MK-8457 is a novel inhibitor of spleen tyrosine kinase (SYK) and zeta-chain-associated protein kinase 70 (ZAP70) that is being investigated as an RA treatment.
BI1002494 Chemical Structure
 BCP24161 BI1002494 1319738-39-0
BI1002494 is a potent and selective Syk inhibitor. It acts by protecting mice from arterial thrombosis and thromboinflammatory brain infarction.
SRX3207 Chemical Structure
 BCP40266 SRX3207 2254693-15-5
SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively.
Gusacitinib hydrochloride Chemical Structure
 BCP35707 Gusacitinib hydrochloride 2228989-14-6
Gusacitinib (ASN-002) is an orally active and potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
Gusacitinib HCl Chemical Structure
 BCP31676 Gusacitinib HCl GusacitinibHCl
Gusacitinib (ASN-002) is a potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
Gusacitinib Chemical Structure
 BCP31675 Gusacitinib 1425381-60-7
Gusacitinib (ASN-002) is a potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM.
Lanraplenib Chemical Structure
 BCP30292 Lanraplenib 1800046-95-0
GS-9876 is a novel, highly selective, SYK Inhibitor.
R 112 Chemical Structure
 BCP20695 R 112 575474-82-7
R112 is an ATP-competitive inhibitor of Syk kinase with a Ki of 96 nM. R112 inhibits Syk kinase activity with an IC50 of 226 nM.
RO 9021 Chemical Structure
 BCP17963 RO 9021 1446790-62-0
RO9021 is an oral, ATP-competative and selective inhibitor of spleen tyrosine kinase (SYK). RO-9021 potently inhibited SYK kinase activity with an average IC50 of 5.6 nM.
PRT-060318 Chemical Structure
 BCP13151 PRT-060318 1194961-19-7
PRT-060318 (PRT318,P142–76) is a novel selective inhibitor of the tyrosine kinase Syk with an IC50 of 4 nM.
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