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Survivin

Chemical Structure Cat. No. Product Name CAS No.
LQZ-7I Chemical Structure
 BCP43515 LQZ-7I 195822-23-2
LQZ-7I is a survivin-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.
YM-155 hydrochloride Chemical Structure
 BCP35549 YM-155 hydrochloride 355406-09-6
YM155 is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM.
GDP366 Chemical Structure
 BCP30719 GDP366 501698-03-9
GDP366, a dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.
FL118 Chemical Structure
 BCP12571 FL118 151636-76-9
FL118 is an inhibitor of human survivin expression, activating tumor suppressor p53 as a novel MOA in p53 wild-type cancer cells.
Sepantronium Bromide Chemical Structure
 BCP01864 Sepantronium Bromide 781661-94-7
Sepantronium bromide(YM155) is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.
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