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Integrase

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Integrase

Chemical Structure Cat. No. Product Name CAS No.
BMS-538203 Chemical Structure
 BCP10394 BMS-538203 543730-41-2
BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent.
Bictegravir Chemical Structure
 BCP25703 Bictegravir 1611493-60-7
Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
Bictegravir Sodium Chemical Structure
 BCP20910 Bictegravir Sodium 1807988-02-8
Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile.
Cabotegravir Chemical Structure
 BCP08631 Cabotegravir 1051375-10-0
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. Cabotegravir is an inhibitor of OAT1 (IC50 0.81 μM) and OAT3 (IC50 0.41 μM).
Cabotegravir Sodium Chemical Structure
 BCP24687 Cabotegravir Sodium 1051375-13-3
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. Cabotegravir is an inhibitor of OAT1 (IC50 0.81 μM) and OAT3 (IC50 0.41 μM).
Dolutegravir sodium Chemical Structure
 BCP11890 Dolutegravir sodium 1051375-19-9
Dolutegravir sodium salt is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Raltegravir Chemical Structure
 BCP01394 Raltegravir 518048-05-0
Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection.
Dolutegravir Chemical Structure
 BCP02329 Dolutegravir 1051375-16-6
Dolutegravir is an integrase inhibitor being developed for the treatment of human immunodeficiency virus (HIV)-1 infection by GlaxoSmithKline (GSK) on behalf of Shionogi-ViiV Healthcare LLC.
Raltegravir potassium Chemical Structure
 BCP01757 Raltegravir potassium 871038-72-1
Raltegravir Potassium Salt is a potent human immunodeficiency virus (HIV) integrase inhibitor
Elvitegravir Chemical Structure
 BCP01801 Elvitegravir 697761-98-1
Elvitegravir is a human immunodeficiency virus integrase inhibitor with EC50 of 0.7, 2.8 and 1.4 for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD.
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