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Signaling Pathways
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- Epigenetics
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GPCR/G Protein
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Neuro Signaling Pathway
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Protease/Metabolic Enzyme
- COMT
- 11β HSD
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Research Areas
- Metabolic Disease
- Neurological Disease
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Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Azaindazole
- Pyridazine Series
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Boric acid
- Pyrimidine Series
- Quinoline Series
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Benzene Series
- Pyridine Series
Raw Materials
Sirtuin
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
BCP49681 | Nicotinamide riboside malate New | 2415659-01-5 | |
Nicotinamide riboside malate, an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3.
|
BCP48517 | SIRT6 activator 12q New | 2601734-99-8 | |
SIRT6 activator 12q is a novel SIRT6 activator, significantly inhibiting the proliferation and migration of pancreatic ductal adenocarcinoma (PDAC) cells in vitro and markedly suppressing the tumor growth in a PDAC tumor xenograft model.
|
BCP47675 | Decapeptide-12 New | 137665-91-9 | |
Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells.
|
BCP46448 | YK-3-237 New | 1215281-19-8 | |
YK-3-237, a SIRT1 activator, targets mutant p53. YK-3-237 inhibits the proliferation of triple-negative breast cancer cells.
|
BCP41849 | SIRT-IN-2 New | 1431411-66-3 | |
SIRT-IN-2 is a potent inhibitor of SIRT1/2/3, with IC50s of 4, 4, 7 μM, respectively.
|
BCP41219 | Selisistat S-enantiomer New | 848193-68-0 | |
EX-527 S-enantiomer is the S-enantiomer of EX-527, which is a potent and selective SIRT1 inhibitor and with no inhibition on SIRT3 and SIRT3.
|
BCP39800 | SBI-797812 New | 2237268-08-3 | |
SBI-797812 is a novel NAMPT activator, elevating liver NAD+, turning NAMPT into a "super catalyst" that more efficiently generates NMN.
|
BCP37824 | 4'-Bromo-resveratrol New | 1224713-90-9 | |
4'-Bromo-resveratrol is a potent inhibitor of the deacetylases sirtuin 1 (SIRT1) and 3 (SIRT3).
|
BCP37615 | UBCS039 New | 358721-70-7 | |
UBCS039 is the first synthetic Sirt6 activator.
|
BCP37408 | SRT2183 New | 1001908-89-9 | |
SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.
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