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Nature products
Antibodies
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Intermediate
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Raw Materials
Estrogen Receptor
Chemical Structure | Cat. No. | Product Name | CAS No. |
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BCP49307 | OP-1250 New | OP-1250 | |
OP-1250 is a novel oral compound developed to completely antagonize the estrogen receptor (ER) and block the ER-mediated cancer cell growth and proliferation signal.
|
BCP48205 | Camizestrant New | 2222844-89-3 | |
Camizestrant is an orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9833 binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells.
|
BCP23860 | Fispemifene New | 341524-89-8 | |
Fispemifene is a selective estrogen receptor modulator (SERM) potentially for the treatment of hypogonadism.
|
BCP24689 | Endoxifen hydrochloride New | 1197194-41-4 | |
Endoxifen HCl, the active metabolite of Tamoxifen, ia a potent and selective estrogen receptor antagonist. Phase 2.
|
BCP48025 | Methylpiperidino pyrazole New | 289726-02-9 | |
Methylpiperidino pyrazole is a high-affinity and selective ERα antagonist, exhibiting 200-fold potency for ERα over ERβ.
|
BCP48272 | H3B-6545 Hydrochloride New | 2052132-51-9 | |
H3B-6545 Hydrochloride is a selective, oral estrogen receptor covalent antagonist (SERCA).
|
BCP46743 | 2-Hydroxyestrone New | 362-06-1 | |
2-Hydroxyestrone, a specific receptor-mediated antiestrogenic agent with anticarcinogenic activity, inhibits the proliferation of estrogen receptor-positive MCF-7, but not estrogen receptor-negative MDA-MB-231.
|
BCP45881 | ARV-471 New | 2229711-08-2 | |
ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader.
|
BCP38455 | Amcenestrant New | 2114339-57-8 | |
Amcenestrant (SAR439859) is an orally available and nonsteroidal selective estrogen receptor degrader (SERD) with potential antineoplastic activity. SAR439859 is a potent estrogen receptor (ER) antagonist with EC50 of 0.2 nM for ERα degradation.
|
BCP43932 | Giredestrant tartrate New | 2407529-33-1 | |
Giredestrant, also known as GDC-9545 and RG6171, is a SERD.
|