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Apoptosis Pathway

Chemical Structure Cat. No. Product Name CAS No.
MRT-2359 Chemical Structure
 BCP49710 MRT-2359 2803881-11-8
MRT-2359 is an orally active and potent degrader of GSPT1 with anti-tumor activity. MRT-2359 also inhibits the growth of resistant non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) cells. MRT-2359 exhibits preferential activity in MYC-driven cell lines, such as N- and L-MYC high NSCLC and SCLC patient-derived xenografts (PDXs).
Glycochenodeoxycholic acid Chemical Structure
 BCP49686 Glycochenodeoxycholic acid 640-79-9
Glycochenodeoxycholic acid is a bile acid glycine conjugate having 3alpha,7alpha-dihydroxy-5beta-cholan-24-oyl as the bile acid component. It has a role as a human metabolite. It is functionally related to a chenodeoxycholic acid. It is a conjugate acid of a glycochenodeoxycholate.
Brigimadlin Chemical Structure
 BCP49630 Brigimadlin 2095116-40-6
Brigimadlin (BI 907828) is an E3 ubiquitin-protein ligase MDM-2 inhibitor. Brigimadlin serves as an antineoplastic agent.
PC-14586 Chemical Structure
 BCP49506 PC-14586 PC-14586
PC14586 targets p53 Y220C mutants to selectively reactivate p53.
SAR-443820 Chemical Structure
 BCP49450 SAR-443820 SAR-443820
SAR443820 is a central nervous system (CNS)-penetrant small molecule inhibitor of RIPK1.
Chemical Structure
ABD328 Chemical Structure
 BCP49194 ABD328 1055896-19-9
ABD328 is an orally active, small molecule inhibitor of RANKL and TNF signalling that inhibits inflammation in vivo.
DC_AC50 Chemical Structure
 BCP49129 DC_AC50 497061-48-0
DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance.
BCL6-IN-3 Chemical Structure
 BCP49128 BCL6-IN-3 2253878-44-1
BCL6-IN-3 is a potent BCL6 degrader.
Pyridoclax Chemical Structure
 BCP23863 Pyridoclax 1651890-44-6
Pyridoclax is a potential Mcl-1 inhibitor.
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