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Keap1 Nrf2

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Keap1 Nrf2

Chemical Structure Cat. No. Product Name CAS No.
Sappanone A Chemical Structure
 BCP46467 Sappanone A 102067-84-5
Sappanone A is a homoisoflavanone which exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. Sappanone can attenuate allergic airway inflammation in Ovalbumin-induced asthma.
Nrf2 activator-1 Chemical Structure
 BCP45478 Nrf2 activator-1 2230697-41-1
Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 (Nrf2).
NK-252 Chemical Structure
 BCP38773 NK-252 1414963-82-8
NK 252 is a Nrf2 activator. It can induce expression of an antioxidant response element promoter driven reporter gene.
Arimoclomol maleate Chemical Structure
 BCP38423 Arimoclomol maleate 289893-26-1
Arimoclomol is a heat shock protein amplifier. It has been granted Fast Track designation by FDA for the treatment of myotrophic lateral sclerosis (ALS).
Arimoclomol citrate Chemical Structure
 BCP38424 Arimoclomol citrate 368860-21-3
Arimoclomol citrate is a heat shock protein amplifier potentially useful for the treatment of Niemann-Pick disease type C (NP-C).
Arimoclomol Chemical Structure
 BCP38425 Arimoclomol 289893-25-0
Arimoclomol is a heat shock protein amplifier, and is potentially useful for the treatment of Niemann-Pick disease type C (NP-C).
AEM1 Chemical Structure
 BCP37859 AEM1 1030123-90-0
AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.
KI696 Chemical Structure
 BCP33044 KI696 1799974-70-1
KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction.
4-Octyl Itaconate Chemical Structure
 BCP31060 4-Octyl Itaconate 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Ezetimibe Ketone Chemical Structure
 BCP09273 Ezetimibe Ketone 191330-56-0
Ezetimibe Ketone is Phase-I metabolite of Ezetimibe.Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.
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