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MAP3K

Chemical Structure Cat. No. Product Name CAS No.
ASK1-IN-2 Chemical Structure
 BCP48906 ASK1-IN-2 2541792-70-3
ASK1-IN-2 is a potent and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with an IC50 of 32.8 nM.
PF-05381941 Chemical Structure
 BCP45842 PF-05381941 1474022-02-0
PF-05381941 is a novel potent dual TAK1/p38a inhibitor.
5Z-7-Oxozeaenol Chemical Structure
 BCP34467 5Z-7-Oxozeaenol 253863-19-3
5Z-7-Oxozeaenol is a covalent inhibitor that acts against the several protein kinases (e.g. ERK2 and TAK1) that possess a free cysteine at the gatekeeper-2 position.
TAK1/MAP4K2 inhibitor 1 Chemical Structure
 BCP21395 TAK1/MAP4K2 inhibitor 1 1315330-11-0
TAK1/MAP4K2 inhibitor 1 is a B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases.
GNE-3511 Chemical Structure
 BCP19925 GNE-3511 1496581-76-0
GNE-3511 is a potent and selective zipper kinase (DLK, MAP3K12) inhibitors.
ASK1IN1 Chemical Structure
 BCP19368 ASK1IN1 1262041-49-5
ASK1-IN-1 is an apoptosis signal regulating kinase 1 (ASK1) inhibitor extracted from patent WO2016025474A1, Compound 4.
NQDI-1 Chemical Structure
 BCP16684 NQDI-1 175026-96-7
NQDI-1 inhibits apoptosis signal-regulating kinase 1 (ASK1) with a Ki of 500 nM.
NG-25 Chemical Structure
 BCP28600 NG-25 1315355-93-1
NG25 is a potent dual TAK1 and MAP4K2 inhibitor.
Selonsertib Chemical Structure
 BCP17814 Selonsertib 1448428-04-3
Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with a pIC50 of 8.3±0.07.
GS-4997 HCl salt Chemical Structure
 BCP20629 GS-4997 HCl salt 1448428-05-4
Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.
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