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HMGCR

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HMGCR

Chemical Structure Cat. No. Product Name CAS No.
SR 12813 Chemical Structure
 BCP25726 SR 12813 126411-39-0
SR12813 is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM.
Pravastatin Chemical Structure
 BCP21480 Pravastatin 81093-37-0
Pravastatin is a HMG-CoA Reductase Inhibitor. The mechanism of action of pravastatin is as a Hydroxymethylglutaryl-CoA Reductase Inhibitor.
Cerivastatin Sodium Chemical Structure
 BCP21297 Cerivastatin Sodium 143201-11-0
Cerivastatin Sodium is the sodium salt of cerivastatin, a synthetic lipid-lowering agent.
Cerivastatin Chemical Structure
 BCP24254 Cerivastatin 145599-86-6
Cerivastatin is a statins used to lower cholesterol and prevent cardiovascular disease. It was marketed by the pharmaceutical company Bayer A.G. in the late 1990s. Cerivastatin was voluntarily withdrawn from the market worldwide in 2001, due to reports of fatal rhabdomyolysis. During postmarketing surveillance, 52 deaths were reported in patients using Cerivastatin, mainly from rhabdomyolysis and its resultant renal failure.
Tert-butyl rosuvastatin Chemical Structure
 BCP13063 Tert-butyl rosuvastatin 355806-00-7
Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin a selective, competitive HMG-CoA reductase inhibitor.
Rosuvastatin sodium Chemical Structure
 BCP12749 Rosuvastatin sodium 147098-18-8
Rosuvastatin Sodium Salt.Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase
Pitavastatin lactone Chemical Structure
 BCP11656 Pitavastatin lactone 141750-63-2
Pitavastatin (NK-104) is a potent HMG-CoA reductase inhibitor, Pitavastatin inhibited cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in a human liver cancer cell line (HepG2).
Clinofibrate Chemical Structure
 BCP13269 Clinofibrate 30299-08-2
Clinofibrate is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
Pravastatin sodium Chemical Structure
 BCP13374 Pravastatin sodium 81131-70-6
Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Mevastatin Chemical Structure
 BCP12101 Mevastatin 73573-88-3
Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans.
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