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DUB

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DUB

Chemical Structure Cat. No. Product Name CAS No.
RA-9 Chemical Structure
 BCP48946 RA-9 919091-63-7
RA-9 is a cell permeable and potent inhibitor of the ubiquitin-proteasome system (UPS). RA-9 Inhibits Proteasome-Associated DUBs and Ovarian Cancer in Vitro and in Vivo via Exacerbating Unfolded Protein Responses.
USP7-IN-1 Chemical Structure
 BCP47280 USP7-IN-1 1381291-36-6
USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer.
Gly-AMC HCl Chemical Structure
 BCP47049 Gly-AMC HCl 208459-17-0
Gly-AMC, also known as L-Gly-7-Amino-4-Methylcoumarin, is a probe and chromphore substrate for aminopeptidase.
USP7-IN-6 Chemical Structure
 BCP46579 USP7-IN-6 2166586-47-4
USP7-IN-6 is a potent ubiquitin specific protease 7 (USP7) inhibitor with an IC50 of 6.8 nM.
KSQ-4279 Chemical Structure
 BCP46572 KSQ-4279 2446480-97-1
KSQ-4279 is a USP1 and PARP inhibitor.
DUBs-IN-2 Chemical Structure
 BCP46476 DUBs-IN-2 924296-19-5
DUBs-IN-2 is a potent deubiquitinase enzyme inhibitor with IC50s of 7.2 uM/0.93 uM for USP7/USP8 respectively.
MF094 Chemical Structure
 BCP45453 MF094 2241025-68-1
MF-094 is a potent and selective USP30 inhibitor. MF-094 increases protein ubiquitination and accelerates mitophagy.
GNE-6776 Chemical Structure
 BCP45102 GNE-6776 2009273-71-4
GNE-6776 is a novel potent, specific, non-covalent, orally bioavailable USP7 inhibitor with IC50 of 1.34 uM .
GNE-6640 Chemical Structure
 BCP41857 GNE-6640 2009273-60-1
GNE-6776 is a potent and non-covalent USP7 inhibitor with IC50 of 1.34 uM. GNE-6776 targets cellular USP7, MDM2, and p53 signalling pathways, and induces tumor cell death.
XL177A Chemical Structure
 BCP40918 XL177A 2417089-74-6
XL177A is a potent USP7 inhibitor.
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