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TAK1

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TAK1

Chemical Structure Cat. No. Product Name CAS No.
HG6-64-1 Chemical Structure
 BCP11080 HG6-64-1 1315329-43-1
HG6-64-1 is a potent and selective B-Raf and mutant B-Raf inhibitor.HG6-64-1 is a potent dual TAK1 and MAP4K2 ((germinal center kinase, GCK)) inhibitor with IC50 of 41 nM and 98 nM, respectively.
NG-25 Chemical Structure
 BCP28600 NG-25 1315355-93-1
NG25 is a potent dual TAK1 and MAP4K2 inhibitor.
Triptolide Chemical Structure
 BCP01915 Triptolide 38748-32-2
Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
LL Z1640-2 Chemical Structure
 BCP09951 LL Z1640-2 66018-38-0
LL-Z 1640-2 is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of TAK1 and VEGF-R2, with IC50s of 8 nM and 52 nM, respectively.
Takinib Chemical Structure
 BCP20873 Takinib 1111556-37-6
Takinib is a potent and selective TAK1 inhibitor with an IC50 of 9.5 nM.
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