TAN 1364B
| CAS No. | 154639-24-4 | Cat. No. | BCP44603 |
| Name | TAN 1364B | ||
| Synonyms | RK-682 (rac-1); Streptomyces sp.; | ||
| Formula | C21H36O5 | M. Wt | 368.51 |
| Description | TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682. TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B, but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium. TAN 1364B forms aggregates in solution and binds to both the PTP binding site and to protein surfaces. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Phosphatase | ||
Structure
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