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TLR

Chemical Structure Cat. No. Product Name CAS No.
Vidutolimod Chemical Structure
 BCP49433 Vidutolimod 147063-80-7
Vidutolimod (CMP-001) is a Toll-like receptor 9 (TLR9) agonist, with the ability to generate tumor-targeted T cells capable of killing a tumor both locally and systemically in combination with checkpoint inhibitors (nivolumab, in this case), thus potentially improving outcomes for people whose tumors are progressing.
Cavrotolimod Chemical Structure
 BCP49374 Cavrotolimod 2378664-12-9
Cavrotolimod (AST-008) is an SNA toll-like receptor 9 (TLR9) agonist designed to robustly activate innate and adaptive immune responses.
Paridiprubart Chemical Structure
 BCP47433 Paridiprubart 2641646-59-3
Paridiprubart is an immunoglobulin G1-kappa, anti-[Homo sapiens TLR4 (toll like receptor 4, toll-like receptor 4, CD284)], humanized monoclonal antibody.
Pam3CSK4 TFA Chemical Structure
 BCP48883 Pam3CSK4 TFA 112208-01-2
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2.
Enpatoran hydrochloride Chemical Structure
 BCP48403 Enpatoran hydrochloride 2101945-93-9
Enpatoran Hydrochloride is a potent and orally active inhibitor of TLR7/8, with IC50s of 11.1 nM and 24.1 nM in HEK293 cells.
TLR7/8-IN-1 Chemical Structure
 BCP48001 TLR7/8-IN-1 2205095-75-4
TLR7/8-IN-1 is a crystalline from of a TLR7/TLR8 inhibitor extracted from patent WO2019220390, compound 2b.
Sparstolonin B Chemical Structure
 BCP44673 Sparstolonin B 1259330-61-4
Sparstolonin B is a potent TLR2 and TLR4 antagonist, exhibiting anti-inflammatory and anti-viral (anti-HIV) properties.
Afimetoran Chemical Structure
 BCP44088 Afimetoran 2171019-55-7
Afimetoran is a toll-like receptor antagonist and immunomodulator.
Imiquimod hydrochloride Chemical Structure
 BCP42840 Imiquimod hydrochloride 99011-78-6
Imiquimod hydrochloride, an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist.
Glycopyranoside lipid A Chemical Structure
 BCP39685 Glycopyranoside lipid A 1246298-63-4
Monophosphoryl Lipid A is a toll-like receptor 4 agonist with potential immunostimulatory activity, which is commonly used as a vaccine adjuvant.
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