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DHFR

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DHFR

Chemical Structure Cat. No. Product Name CAS No.
Piritrexim Chemical Structure
 BCP29680 Piritrexim 72732-56-0
Piritrexim is a lipid-soluble inhibitor of dihydrofolate reductase (DHFR) that appears to be an active agent in patients with metastatic urothelial cancer when administered as a 5-day, low-dose oral schedule.
Trimethoprim Chemical Structure
 BCP12148 Trimethoprim 738-70-5
Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections.
Aditoprim Chemical Structure
 BCP19328 Aditoprim 56066-63-8
Aditoprim is an antibacterial dihydrofolate reductase inhibitor.
(+/-)Amethopterin Chemical Structure
 BCP29918 (+/-)Amethopterin 60388-53-6
Amethopterin is a chemotherapy agent and immune system suppressant.
Calcium levofolinate Chemical Structure
 BCP06607 Calcium levofolinate 80433-71-2
Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.
5-Methyltetrahydrofolate calcium Chemical Structure
 BCP29923 5-Methyltetrahydrofolate calcium 26560-38-3
Calcium N5-methyltetrahydrofolate(NSC173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease and advanced cancers such as breast and colorectal cancers.
Levomefolic Acid Chemical Structure
 BCP29924 Levomefolic Acid 31690-09-2
Levomefolic acid (5-MTHF) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions.
Abitrexate Chemical Structure
 BCP02078 Abitrexate 59-05-2
Methotrexate is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.
Methotrexate hydrate Chemical Structure
 BCP13701 Methotrexate hydrate 133073-73-1
Methotrexate ,analog of folic acid, is a nonspecific inhibitor of the dihydrofolate reductase(DHFR) of bacteria and cancerous cells as well as normal cells.
Methotrexate disodium salt Chemical Structure
 BCP13700 Methotrexate disodium salt 7413-34-5
Methotrexate disodium is an organic sodium salt that is the disodium salt of methotrexate. It has a role as an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It contains a methotrexate(2-).
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