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CAS No. | 314291-83-3 | Cat. No. | BCP44181 |
Name | PHPS1 | ||
Synonyms | PHPS 1; PHPS-1; | ||
SMILES | C1=CC=C(C=C1)N2C(=O)C(=C(N2)C3=CC=C(C=C3)[N+](=O)[O-])N=NC4=CC=C(C=C4)S(=O)(=O)O | ||
Chemical Name | |||
Formula | C21H15N5O6S | M. Wt | 465.44 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PHPS1 is an inhibitor of the protein tyrosine phosphatase Shp2. PHPS1 also efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines. |
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