KY19382 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2226664-93-1 | Cat. No. | BCP38332 |
| Name | KY19382 | ||
| Synonyms | KY-19382;KY 19382; | ||
| SMILES | CON=C1C2=CC=CC=C2N=C1C3=C(NC4=CC(=C(C=C43)Cl)Cl)O | ||
| Chemical Name | |||
| Formula | C17H11Cl2N3O2 | M. Wt | 360.19 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases. | ||
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