KY19382
| CAS No. | 2226664-93-1 | Cat. No. | BCP38332 |
| Name | KY19382 | ||
| Synonyms | KY-19382;KY 19382; | ||
| Formula | C17H11Cl2N3O2 | M. Wt | 360.19 |
| Description | KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases. | ||
| Pathways | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 | ||
Structure
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