VP3.15 dihydrobromide New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1281681-33-1 | Cat. No. | BCP31222 |
| Name | VP3.15 dihydrobromide | ||
| Synonyms | VP-3.15 dihydrobromide;VP3.15 2HBr;VP-3.15 2HBr; | ||
| SMILES | [H]Br.[H]Br.N1(CC/N=C2N=C(C3=CC=CC=C3)N(C4=CC=CC=C4)S/2)CCOCC1 | ||
| Chemical Name | |||
| Formula | C20H24Br2N4OS | M. Wt | 528.30 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | VP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 dihydrobromide has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). | ||
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