CHF 5074 New
Data Sheet
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| CAS No. | 749269-83-8 | Cat. No. | BCP30410 |
| Name | CHF 5074 | ||
| Synonyms | CHF-5074; CHF5074; Itanapraced; CSP-1103; CSP1103; CSP 1103; | ||
| SMILES | C1CC1(C2=CC(=C(C=C2)C3=CC(=C(C=C3)Cl)Cl)F)C(=O)O | ||
| Chemical Name | |||
| Formula | C16H11Cl2FO2 | M. Wt | 325.16 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CHF-5074 is a γ-secretase modulator. CHF-5074 reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 μM respectively. CHF5074 reduces brain beta-Amyloid pathology in a transgenic mouse model of Alzheimer's Disease without causing peripheral toxicity. CHF5074 is a non-steroidal anti-inflammatory derivative holding disease-modifying potential for the treatment of Alzheimer's disease. | ||
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