Begacestat New
Data Sheet
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| CAS No. | 769169-27-9 | Cat. No. | BCP46406 |
| Name | Begacestat | ||
| Synonyms | GSI-953; GSI953; GSI 953; | ||
| SMILES | C1=C(SC(=C1)Cl)S(=O)(=O)NC(CO)C(C(F)(F)F)C(F)(F)F | ||
| Chemical Name | |||
| Formula | C9H8ClF6NO3S2 | M. Wt | 391.74 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Begacestat, also known as GSI-953, is a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease. Begacestat inhibits Abeta production with low nanomolar potency in cellular and cell-free assays of gamma-secretase function. | ||
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