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SN-38-D3 Chemical Structure

SN-38-D3

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49629CAS No. :718612-49-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 718612-49-8 Cat. No. BCP49629
Name SN-38-D3
Synonyms NK012-D3;[2H3]-SN-38;
SMILES CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)O
Chemical Name
Formula C22H20N2O5 M. Wt 392.4
Purity 98% Storage Store at 4-8°C
Description SN-38-D3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively.
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