Banoxantrone dihydrochloride New
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CAS No. | 252979-56-9 | Cat. No. | BCP31589 |
Name | Banoxantrone dihydrochloride | ||
Synonyms | Banoxantrone 2HCl;AQ4N dihydrochloride; | ||
SMILES | C[N+](C)(CCNC1=C2C(=C(C=C1)NCC[N+](C)(C)[O-])C(=O)C3=C(C=CC(=C3C2=O)O)O)[O-].Cl.Cl | ||
Chemical Name | |||
Formula | C22H30Cl2N4O6 | M. Wt | 517.40 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Banoxantrone dihydrochloride, a bioreductive prodrug, can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor, and exhibits little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 >100 μM). |
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