Chebulanin

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP28487CAS No. ：166833-80-3Purity：98%

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CAS No.	166833-80-3	Cat. No.	BCP28487
Name	Chebulanin
Synonyms	Terminalic acid;
SMILES	C1=C(C=C(C(=C1O)O)O)C(=O)OC2C3C(C(C(O2)CO)OC(=O)C(C4C(C(=O)OC5=C4C(=CC(=C5O)O)C(=O)O3)O)CC(=O)O)O
Chemical Name
Formula	C27H24O19	M. Wt	652.47
Purity	98%	Storage	Store at 4-8°C
Description	Chebulanin is a topoisomerase I inhibitor. Chebulanin inhibits the calcineurin pathway in C. neoformans.Chebulanin exhibits potent antifungal activity against various human pathogenic fungi with minimum inhibitory concentrations ranging from 0.25 to over 64 μg/ml. Chebulanin suppresses the expression of inflammatory mediators and prevents cartilage destruction and bone erosion in mice, therefore, chebulanin is a strong therapeutic alternative for the treatment of rheumatism arthritis.Chebulanin shows strong radical scavenging activity, good potency to chelate Fe2⁺ and good inhibition ability of lipid peroxidation. Chebulanin has apparent capacities of inhibiting the survival of MCF-7 human cancer cell line.