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Cinaciguat hydrochloride Chemical Structure

Cinaciguat hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30226CAS No. :646995-35-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 646995-35-9 Cat. No. BCP30226
Name Cinaciguat hydrochloride
Synonyms Cinaciguat HCl;BAY 58-2667 hydrochloride;BAY 582667; BAY-582667; BAY582667; BAY 58-2667; BAY-58-2667; BAY58-2667;
SMILES C1=CC=C(C=C1)CCC2=CC=C(C=C2)COC3=CC=CC=C3CCN(CCCCC(=O)O)CC4=CC=C(C=C4)C(=O)O.Cl
Chemical Name
Formula C36H40ClNO5 M. Wt 602.17
Purity 98% Storage Store at 4-8°C
Description Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets.Cinaciguat, also known as BAY582667 or BAY58-2667, is a soluble guanylate cyclase activator. Cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus. Cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats. Cinaciguat prevents neointima formation after arterial injury by decreasing vascular smooth muscle cell migration and proliferation.
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