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Plecanatide Chemical Structure

Plecanatide

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25087CAS No. :467426-54-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 467426-54-6 Cat. No. BCP25087
Name Plecanatide
Synonyms SP-304; SP 304; SP304; Trulance;
SMILES
Chemical Name
Formula C65H104N18O26S4 M. Wt 1681.89
Purity 98% Storage Store at 4-8°C
Description Plecanatide is a structural analog of human uroguanylin, and similarly to uroguanylin, plecanatide functions as a guanylate cyclase-C (GC-C) agonist. Both plecanatide and its active metabolite bind to GC-C and act locally on the luminal surface of the intestinal epithelium. Activation of GC-C results in an increase in both intracellular and extracellular concentrations of cyclic guanosine monophosphate (cGMP).
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