Cinaciguat hydrochloride
| CAS No. | 646995-35-9 | Cat. No. | BCP30226 |
| Name | Cinaciguat hydrochloride | ||
| Synonyms | Cinaciguat HCl;BAY 58-2667 hydrochloride;BAY 582667; BAY-582667; BAY582667; BAY 58-2667; BAY-58-2667; BAY58-2667; | ||
| Formula | C36H40ClNO5 | M. Wt | 602.17 |
| Description | Cinaciguat hydrochloride is a potent soluble guanylate cyclase (GC) activator with EC50 of 15 nM in platelets.Cinaciguat, also known as BAY582667 or BAY58-2667, is a soluble guanylate cyclase activator. Cinaciguat prevents cardiac dysfunction in a rat model of type-1 diabetes mellitus. Cinaciguat exert no direct effects on contractility and relaxation of cardiac myocytes from normal rats. Cinaciguat prevents neointima formation after arterial injury by decreasing vascular smooth muscle cell migration and proliferation. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Guanylate Cyclase | ||
Structure
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