N-Desethyl Sunitinib
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CAS No. | 356068-97-8 | Cat. No. | BCP20914 |
Name | N-Desethyl Sunitinib | ||
Synonyms | SU11662;SU 11662;SU-11662; | ||
SMILES | O=C1NC2=CC=C(F)C=C2/C1=C/C3=C(C)C(C(NCCNCC)=O)=C(C)N3 | ||
Chemical Name | |||
Formula | C20H23FN4O2 | M. Wt | 370.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | N-Desethyl Sunitinib is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. |
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