N-Desethyl Sunitinib
| CAS No. | 356068-97-8 | Cat. No. | BCP20914 |
| Name | N-Desethyl Sunitinib | ||
| Synonyms | SU11662;SU 11662;SU-11662; | ||
| Formula | C20H23FN4O2 | M. Wt | 370.42 |
| Description | N-Desethyl Sunitinib is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | PDGFR VEGFR | ||
Structure
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