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CAS No. | 1164462-05-8 | Cat. No. | BCP25837 |
Name | TG4-155 | ||
Synonyms | TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155; | ||
SMILES | CC1=CC2=CC=CC=C2N1CCNC(=O)C=CC3=CC(=C(C(=C3)OC)OC)OC | ||
Chemical Name | |||
Formula | C23H26N2O4 | M. Wt | 394.47 |
Purity | 98% | Storage | Store at 4-8°C |
Description | TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor. |
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