TG4-155
CAS No. | 1164462-05-8 | Cat. No. | BCP25837 |
Name | TG4-155 | ||
Synonyms | TG-4-155; TG 4-155; TG4155; TG-4155; TG 4155; | ||
Formula | C23H26N2O4 | M. Wt | 394.47 |
Description | TG4-155 is a potent, brain-permeant and selective EP2 receptor antagonist with a Ki of 9.9 nM. TG4-155 shows low nanomolar antagonist activity against only EP2 and DP1. TG4-155 has an EP2 Schild KB of 2.4 nM and displays 550-4750-fold selectivity for EP2 over EP1, EP3, EP4 and IP, but only 14-fold selectivity against the DP1 receptor. | ||
Pathways | GPCR/G Protein | ||
Targets | Prostaglandin Receptor |
Structure
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