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U-46619 Chemical Structure

U-46619

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP39866CAS No. ：56985-40-1Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 56985-40-1 Cat. No. BCP39866
Name U-46619
Synonyms U 46619;U46619;
SMILES CCCCCC(C=CC1C2CC(C1CC=CCCCC(=O)O)CO2)O
Chemical Name
Formula C21H34O4 M. Wt 350.49
Purity 98% Storage Store at 4-8°C
Description U46619 is a PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM). U46619 potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. It activates ERK-1 and ERK-2 in HEK 293 cells expressing TPα and TPβ receptors.
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