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CAS No. | 52549-17-4 | Cat. No. | BCP11947 |
Name | Pranoprofen | ||
Synonyms | Pyranoprofen;Niflan;Oftalar; | ||
SMILES | |||
Chemical Name | |||
Formula | C15H13NO3 | M. Wt | 255.27 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Pranoprofen inhibited ER stress-induced glucose regulated protein 78 (GRP78) expression, an ER-localized molecular chaperon. Moreover, pranoprofen inhibited ER stress-induced CCAAT/enhancer-binding protein homologous protein (CHOP) expression, an apoptotic transcription factor. the inhibitory effect of pranoprofen on ER stress-related genes (GRP78 and CHOP) would be mediated through the inhibition of XBP-1 splicing . |
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