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CAS No. | 519187-97-4 | Cat. No. | BCP33233 |
Name | Edonerpic maleate | ||
Synonyms | T-817 maleate; T-817MA;T817 maleate; T817MA;T 817 maleate; T 817MA; | ||
SMILES | C1C(CN1CCCOCCC2=CC3=C(C=C2)SC=C3)O.C(=CC(=O)O)C(=O)O | ||
Chemical Name | |||
Formula | C20H25NO6S | M. Wt | 407.48 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Edonerpic maleate is a novel neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Edonerpic, also known as T-817, is a neuroprotectant. Edonerpic is a candidate therapeutic agent for Alzheimer's disease that inhibits oxidative stress and nitric oxide-induced neurotoxicity and acts as a neurotrophic factor. Edonerpic protects against MPTP-induced neurotoxicity by blocking lipid peroxidation in the SNc, and imply that this compound may be useful for treating neurodegenerative disorders related to oxidative stress, such as Parkinson's disease. |
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