Carboplatin
Data Sheet
For research use only. Not for human use.
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| CAS No. | 41575-94-4 | Cat. No. | BCP22717 |
| Name | Carboplatin | ||
| Synonyms | cis-Diammine(1,1-cyclobutanedicarboxylato)platinum; | ||
| SMILES | O=C(O[Pt]O1)C2(CCC2)C1=O.N.N | ||
| Chemical Name | |||
| Formula | C6H12N2O4Pt | M. Wt | 371.25 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Carboplatin is a second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two ammonia groups and a cyclobutane-dicarboxyl residue. This agent is activated intracellularly to form reactive platinum complexes that bind to nucleophilic groups such as GC-rich sites in DNA, thereby inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These carboplatin-induced DNA and protein effects result in apoptosis and cell growth inhibition. | ||
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