Carboplatin

CAS No.	41575-94-4	Cat. No.	BCP22717
Name	Carboplatin
Synonyms	cis-Diammine(1,1-cyclobutanedicarboxylato)platinum;
Formula	C6H12N2O4Pt	M. Wt	371.25

Description	Carboplatin is a second-generation platinum compound with a broad spectrum of antineoplastic properties. Carboplatin contains a platinum atom complexed with two ammonia groups and a cyclobutane-dicarboxyl residue. This agent is activated intracellularly to form reactive platinum complexes that bind to nucleophilic groups such as GC-rich sites in DNA, thereby inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These carboplatin-induced DNA and protein effects result in apoptosis and cell growth inhibition.
Pathways	Cell Cycle/DNA Damage
Targets	DNA Alkylator/Crosslinker

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