Lanabecestat

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP16986CAS No. ：1383982-64-6Purity：98%

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Chemical Properties&Biological Activity

CAS No.	1383982-64-6	Cat. No.	BCP16986
Name	Lanabecestat
Synonyms	AZD-3293;AZD 3293;LY-3314814;LY 3314814;LY3314814;
SMILES	CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1
Chemical Name
Formula	C26H28N4O	M. Wt	412.53
Purity	98%	Storage	Store at 4-8°C
Description	Lanabecestat, also known as AZD3293 and LY3314814, is a potent, highly permeable, orally active, blood-brain barrier (BBB) penetrating, BACE1 inhibitor with unique slow off-rate kinetics. AZD3293 displayed significant dose- and time-dependent reductions in plasma, cerebrospinal fluid, and brain concentrations of Aβ40, Aβ42, and sAβPPβ.

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