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Atabecestat Chemical Structure

Atabecestat

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25878CAS No. :1200493-78-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1200493-78-2 Cat. No. BCP25878
Name Atabecestat
Synonyms JNJ-54861911; JNJ54861911; JNJ 54861911; RSC-385896; RSC 385896; RSC385896;
SMILES CC1(C=CSC(=N1)N)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)C#N)F
Chemical Name
Formula C18H14FN5OS M. Wt 367.4
Purity 98% Storage Store at 4-8°C
Description Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat (JNJ-54861911) is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment.
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