Lanabecestat
| CAS No. | 1383982-64-6 | Cat. No. | BCP16986 |
| Name | Lanabecestat | ||
| Synonyms | AZD-3293;AZD 3293;LY-3314814;LY 3314814;LY3314814; | ||
| Formula | C26H28N4O | M. Wt | 412.53 |
| Description | Lanabecestat, also known as AZD3293 and LY3314814, is a potent, highly permeable, orally active, blood-brain barrier (BBB) penetrating, BACE1 inhibitor with unique slow off-rate kinetics. AZD3293 displayed significant dose- and time-dependent reductions in plasma, cerebrospinal fluid, and brain concentrations of Aβ40, Aβ42, and sAβPPβ. | ||
| Pathways | Neuro Signaling Pathway | ||
| Targets | Beta secretase | ||
Structure
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