Classified by application

All Products

Signaling Pathways

Angiogenesis/Protein Tyrosine Kinase
- DYRK
- Tie2
- RET
- DDR
- Ephrin Receptor
- Insulin Receptor
- IRAK
- cFMS
- TAM Receptor
- Integrin
- Trk Receptor
- JAK
- PDGFR
- BTK
- VDA
- HIF
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- FAK
- HER2
- EGFR
- c Met
- VEGFR
- FLT3
- c Kit
- IGF1R
- FGFR
- ALK
- Syk
Apoptosis Pathway
- DAPK
- Thymidylate Synthase
- Apoptosis Inducer
- c Myc
- Ferroptosis
- RIP
- PD 1/PD L1
- PKD
- IAP
- p53
- Survivin
- TNF Receptor
- Mdm2
- Caspase
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Cell Cycle/DNA Damage
- LIMK
- Haspin Kinase
- RAD51
- p97
- SRPK
- PAK
- PERK
- eIF
- Mps1
- DNA Alkylator/Crosslinker
- DUB
- HSP
- ROCK
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- Sirtuin
- Casein Kinase
- Wee1
- Topoisomerase
- Microtubule
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- APC
- Telomerase
- PLK
- Antimetabolite
- Aurora
- Kinesin
- PPAR
- HDAC
- DNA/RNA Synthesis
- CDK
- ATM/ATR
- DNA PK
Epigenetics
GPCR/G Protein
Hormone Pathay
Ion Channel/Membrane Transporter
- NKCC
- EAAT
- NCX
- CRAC Channel
- HCN Channel
- GlyT
- URAT1
- BCRP
- Monoamine Transporter
- Chloride Channel
- MCT
- nAChR
- CRM1
- P2 Receptor
- SGLT
- GABA Receptor
- TRP Channel
- Potassium Channel
- Sodium Channel
- Proton Pump
- CFTR
- AMPA/NMDA
- P glycoprotein
- Calcium Channel
- ATPase
Jak/Stat Pathway
- EGFR
- Stat
- JAK
- Pim
MAPK Pathway
- KLF
- MLK
- TOPK
- MAP4K
- MNK
- MAP3K
- RSK
- p38 MAPK
- MEK/ERK
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- Raf
Microbiology/Virology
- Filovirus
- Enterovirus
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- CMV
- Antifungal
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- SARS CoV
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- HCV
- HBV
- HIV
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Neuro Signaling Pathway
NFκB
- Keap1 Nrf2
- MALT1
- TAK1
- NF κB
- IκB/IKK
PI3K/Akt/mTOR
- PI4K
- PTEN
- RSK
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- mTOR
- AKT
- ATM/ATR
- GSK3
- DNA PK
- PDK
- AMPK
- MELK
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- ACC
- Xanthine Oxidase
- Pyruvate Kinase
- Mitochondrial Metabolism
- ALDH
- SCD
- Serine Protease
- MLR
- FTase
- CETP
- Neprilysin
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- PAI1
- NOX
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
TGF beta/Smad
Wnt/Stem Cell
- Hippo
- BMI1
- Gli
- Beta catenin
- Porcupine
- Oct3/4
- PKA
- Stat
- TGFβ/Smad
- ROCK
- Casein Kinase
- JAK
- Notch
- Hedgehog
- Wnt
- Gamma secretase
- GSK3
Others Pathway
- PROTAC
- STING
- Dynamin
- NLR
- AhR
- TLR
- LRRK2
- Vitamin D Related
- Autophagy
- ADC Related
- Interleukin Related
- LpxC
- Others

Research Areas

Nature products

Antibodies

Peptides

Catalysts

Impurities

Intermediate

Raw Materials

Smoothened/Smo

Chemical Structure	Cat. No.	Product Name	CAS No.

	BCP48085	PF-05274857 HCl New	1613439-62-5
	PF-5274857 HCl is a potent and selective smoothened (Smo) receptor antagonist.

	BCP46892	ALLO-2 New	1357350-60-7
	ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.

	BCP46475	MRT10 New	330829-30-6
	MRT-10 is a Smoothened (Smo) receptor antagonist that inhibits ShhN-induced Gli luciferase reporter activity in Shh-light 2 cells and acts as an inverse agonist during nontranscriptional Hedgehog pathway activation.

	BCP46474	MRT-81 New	1263132-08-6
	MRT-81 inhibits human and rodent smoothened Smo receptors effectively with an IC50 value of 41 nM in the Shh-light2 cells.

	BCP25392	Saridegib New	1037210-93-7
	Saridegib is a potent and specific inhibitor of Smoothened (Smo), a key signaling transmembrane protein in the Hedgehog (Hh) pathway.

	BCP23569	XL139 mesylate New	XL139
	BMS-833923, also known as XL-139, is an orally bioavailable small-molecule SMO (Smoothened) inhibitor with potential antineoplastic activity.

	BCP28214	Jervine New	469-59-0
	Jervine(11-Ketocyclopamine) is a naturally occuring steroidal alkaloid that causes cyclopia by blocking sonic hedgehog(Shh) signaling; Jervine is an inhibitor of Smo.