Classified by application
All Products
Signaling Pathways
- Angiogenesis/Protein Tyrosine Kinase
- Apoptosis Pathway
- Cell Cycle/DNA Damage
- Epigenetics
-
GPCR/G Protein
- Urotensin Receptor
- Melatonin Receptor
- Neurotensin Receptor
- Glucose Transporter
- Motilin Receptor
- TGR5
- Cholecystokinin Receptor
- Adenylate Cyclase
- Somatostatin Receptor
- Oxytocin Receptor
- Bradykinin Receptor
- Guanylate Cyclase
- Melanocortin Receptor
- Imidazoline Receptor
- Neuropeptide Receptor
- PAR
- CRFR
- Sigma Receptor
- S1P Receptor
- GHSR
- PKA
- OX Receptor
- Adenosine Receptor
- Glucagon Receptor
- Prostaglandin Receptor
- NK Receptor
- GnRH Receptor
- Leukotriene Receptor
- Glucocorticoid Receptor
- mAChR
- P2 Receptor
- GPR
- CGRP Receptor
- CXCR
- Histamine Receptor
- CaSR
- Ras/Rho
- Vasopressin Receptor
- Smoothened/Smo
- mGluR
- Opioid Receptor
- Dopamine Receptor
- Cannabinoid Receptor
- Angiotensin Receptor
- Adrenergic Receptor
- SGLT
- Endothelin Receptor
- CCR
- 5 HT Receptor/Serotonin Receptor
- Hormone Pathay
- Ion Channel/Membrane Transporter
- Jak/Stat Pathway
- MAPK Pathway
- Microbiology/Virology
-
Neuro Signaling Pathway
- Imidazoline Receptor
- Monoamine Oxidase
- COMT
- Amyloid β
- NK Receptor
- Beta secretase
- AChE
- SSRI
- CaMK
- P glycoprotein
- Opioid Receptor
- Dopamine Receptor
- Adrenergic Receptor
- Histamine Receptor
- mGluR
- Gamma secretase
- Dopamine Transporter
- 5 HT Receptor/Serotonin Receptor
- P2 Receptor
- FAAH
- CGRP Receptor
- nAChR
- COX
- GABA Receptor
- mAChR
- NFκB
- PI3K/Akt/mTOR
-
Protease/Metabolic Enzyme
- COMT
- 11β HSD
- Carboxypeptidase
- ACC
- Xanthine Oxidase
- Pyruvate Kinase
- Mitochondrial Metabolism
- ALDH
- SCD
- Serine Protease
- MLR
- FTase
- CETP
- Neprilysin
- MAGL
- Carbonic Anhydrase
- E1 E2 E3 Enzyme
- Elastase
- PAI1
- NOX
- ROR
- Glucokinase
- Aldose Reductase
- Tyrosinase
- FAS
- DGAT
- Lipoxygenase
- Nampt
- IDO
- IDH
- MMP
- Cathepsin
- Phosphatase
- Thrombin
- FXR
- RAR/RXR
- HMGCR
- FAAH
- Gamma secretase
- RAAS/ACE
- Caspase
- HIV Protease
- Aminopeptidase
- HCV Protease
- HSP
- Tryptophan Hydroxylase/TPH
- Factor Xa
- DPP
- Procollagen C Proteinase
- Integrase
- Phosphodiesterase/PDE
- Phospholipase
- LXR
- Proteasome
- Cytochrome P450
- TGF beta/Smad
- Wnt/Stem Cell
- Others Pathway
Research Areas
- Metabolic Disease
- Neurological Disease
- Endocrinology
- Diabetes
- Cardiovascular Disease
- Immunology
- Allergy
- Inflammation
- Infection
- Cancer
Nature products
Antibodies
Peptides
Catalysts
Impurities
Intermediate
- Amino acid
- Ammonia Series
- Azaindazole
- Pyridazine Series
- Nucleoside Series
- Quinazoline
- Pyrazole Series
- Boric acid
- Pyrimidine Series
- Quinoline Series
- Pyrrole Series
- Thiophene Series
- Saccharide
- Azaindole
- Indole Series
- Piperidine Series
- Indazole Series
- Heterocyclic Series
- Benzene Series
- Pyridine Series
Raw Materials
Pim
Chemical Structure | Cat. No. | Product Name | CAS No. |
---|
BCP43782 | PIM1-IN-1 New | 1417630-95-5 | |
PIM1-IN-1 is a potent and highly selective inhibitor of PIM1/3(IC50s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively),with Antiproliferative and anti-cancer activity.
|
BCP42656 | Parsaclisib hydrochloride New | 1995889-48-9 | |
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes with PIM protein kinase inhibition to cause tumor regression in a model of DLBCL.
|
BCP32632 | NSC31205 New | 6320-51-0 | |
NSC 31205 is a PIM2/1 inhibitor.
|
BCP15861 | TCS PIM-1 1 New | 491871-58-0 | |
TCS PIM-1 1 is a potent and selective ATP-competitive Pim-1 kianse inhibitor with IC50 of 50 nM, displays good selectivity over Pim-2 and MEK1/MEK2(IC50s >20,000 nM).
|
BCP21212 | SMI-4a New | 327033-36-3 | |
SMI-4a, also called as TCS-PIM-1-4a, a thiazolidinedione compound, is a potent, selective ATP-competitive inhibitor against Pim protein kinase (IC50 = 24 nM against Pim-1 and 100 nM against Pim-2) with little or no activity against a panel of 58 other kinase.
|
BCP31128 | PIM447 dihydrochloride New | 1820565-69-2 | |
PIM447 is a pan-PIM kinase ihibitor with Kis of 6, 18, 9 nM for PIM1, PIM2 and PIM3, respectively.
|
BCP27625 | Pim1/AKK1-IN-1 New | 1093222-27-5 | |
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
|
BCP13641 | LGB321 New | 1210415-88-5 | |
LGB-321 is a potent and selective ATP-competitive small molecule inhibitor of PIM kinases (Pan-PIM kinase inhibitor).
|
BCP30070 | TP-3654 New | 1361951-15-6 | |
TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively.
|
BCP24206 | LGH447 Hydrochloride | 1210416-52-6 | |
LGH447 Hydrochloride is Potent and specific pan-PIM inhibitor, inhibiting proliferation of several AML cell lines, showing dual antitumoral and bone antiresorptive effects.
|