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nAChR

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nAChR

Chemical Structure Cat. No. Product Name CAS No.
BNC-210 Chemical Structure
 BCP49244 BNC-210 1020634-41-6
BNC210 is an anxiolytic drug that acts via negative allosteric modulation of the α7-nicotinic acetylcholine receptor.
AR-R17779 Chemical Structure
 BCP24016 AR-R17779 178419-47-1
AR-R17779 is a selective alpha7 nicotinic agonist (Ki values are 190 and 16000 nM for rat α7 and α4β2 receptors respectively).
Tebanicline tosylate Chemical Structure
 BCP25229 Tebanicline tosylate 198283-74-8
Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects.
Tebanicline benzoate Chemical Structure
 BCP25230 Tebanicline benzoate 209326-18-1
Tebanicline represents a novel class of broad-spectrum analgesics whose primary mechanism of action is activation of the neuronal nicotinic acetylcholine receptors.
Tebanicline dihydrochloride Chemical Structure
 BCP25231 Tebanicline dihydrochloride 209326-19-2
Tebanicline dihydrochloride is a nAChR modulator with potent, orally effective analgesic activity.
Myosmine Chemical Structure
 BCP47943 Myosmine 532-12-7
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM.
NS1738 Chemical Structure
 BCP46794 NS1738 501684-93-1
NS1738 is a α7 positive allosteric modulator.
Anagyrin Chemical Structure
 BCP44368 Anagyrin 486-89-5
Anagyrine is an alkaloid that has been found in L. albus and has nematocidal and anticancer activities.
ABT-418 hydrochloride Chemical Structure
 BCP38433 ABT-418 hydrochloride 147388-83-8
ABT-418 hydrochloride is a neuronal nicotinic acetylcholine receptor agonist.
4BP-TQS Chemical Structure
 BCP37825 4BP-TQS 360791-49-7
4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs).
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