Glycyl-H 1152 dihydrochloride New
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CAS No. | 913844-45-8 | Cat. No. | BCP27782 |
Name | Glycyl-H 1152 dihydrochloride | ||
Synonyms | H-1152Glycyl, Dihydrochloride; Rho Kinase Inhibitor IV; | ||
SMILES | CC1CN(CCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C)C(=O)CN.Cl.Cl | ||
Chemical Name | |||
Formula | C18H24N4O3S.2HCl | M. Wt | 449.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Glycyl-H 1152 dihydrochloride is a glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride with an improved selectivity for ROCKII (IC50 = 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC, respectively). Glycyl-H 1152 dihydrochloride is used for the treatment of hypertension and arteriosclerosis. |
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