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SEW​2871 Chemical Structure

SEW​2871

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35038CAS No. :256414-75-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 256414-75-2 Cat. No. BCP35038
Name SEW​2871
Synonyms SEW 2871; SEW-2871;
SMILES C1=CC=C(C=C1)C2=C(SC(=C2)C3=NC(=NO3)C4=CC(=CC=C4)C(F)(F)F)C(F)(F)F
Chemical Name
Formula C20H10F6N2OS M. Wt 440.36
Purity 98% Storage Store at 4-8°C
Description SEW2871 is a S1P1 agonist (sphingosine-1-phosphate type 1 receptor agonist). SEW2871 improves cognitive function in Alzheimer's disease model rats. SEW2871 prolongs heterotopic heart allograft survival in mice. SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. SEW2871 prolongs heterotopic heart allograft survival in mice.
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