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BAY-3827 Chemical Structure

BAY-3827

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46774CAS No. :2377576-35-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2377576-35-5 Cat. No. BCP46774
Name BAY-3827
Synonyms BAY3827;BAY 3827;
SMILES CCC1=CC=CC=C1C(=O)NC2=NNC3=C(C(=C(C=C32)C4C(=C(N(C(=C4C#N)C)C)C)C#N)F)C
Chemical Name
Formula C27H25FN6O M. Wt 468.53
Purity 98% Storage Store at 4-8°C
Description BAY-3827 is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors.BAY-3827 strongly inhibits Acetyl-CoA carboxylase (ACC) phosphorylation in COLO 320DM and IMR-32 cells, but fails to inhibit the proliferation of cells with dysregulated c-MYC or N-MYC.
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