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CAS No. | 2377576-35-5 | Cat. No. | BCP46774 |
Name | BAY-3827 | ||
Synonyms | BAY3827;BAY 3827; | ||
SMILES | CCC1=CC=CC=C1C(=O)NC2=NNC3=C(C(=C(C=C32)C4C(=C(N(C(=C4C#N)C)C)C)C#N)F)C | ||
Chemical Name | |||
Formula | C27H25FN6O | M. Wt | 468.53 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BAY-3827 is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors.BAY-3827 strongly inhibits Acetyl-CoA carboxylase (ACC) phosphorylation in COLO 320DM and IMR-32 cells, but fails to inhibit the proliferation of cells with dysregulated c-MYC or N-MYC. |
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