BAY-3827
| CAS No. | 2377576-35-5 | Cat. No. | BCP46774 |
| Name | BAY-3827 | ||
| Synonyms | BAY3827;BAY 3827; | ||
| Formula | C27H25FN6O | M. Wt | 468.53 |
| Description | BAY-3827 is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors.BAY-3827 strongly inhibits Acetyl-CoA carboxylase (ACC) phosphorylation in COLO 320DM and IMR-32 cells, but fails to inhibit the proliferation of cells with dysregulated c-MYC or N-MYC. | ||
| Pathways | PI3K/Akt/mTOR Epigenetics | ||
| Targets | AMPK | ||
Structure
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