LY-3200882
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CAS No. | 1898283-02-7 | Cat. No. | BCP20882 |
Name | LY-3200882 | ||
Synonyms | LY 3200882; LY3200882; | ||
SMILES | CC(C)(C1=NC=CC(=C1)NC2=NC=CC(=C2)OC3=CN(N=C3C4CCOCC4)C5CC5)O | ||
Chemical Name | |||
Formula | C24H29N5O3 | M. Wt | 435.52 |
Purity | 98% | Storage | Store at 4-8°C |
Description | LY-3200882 is an orally active TGFbeta inhibitor. LY3200882 targets transforming growth factor-beta (TGFb), with potential antineoplastic activity. Upon administration, LY3200882 specifically targets and binds to TGFb, which prevents both the binding of TGFb to its receptor TGFbR and TGFb-mediated signal transduction. This may lead to a reduction in TGFb-dependent proliferation of cancer cells. |
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